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Guanfacine hydrochloride

CAT: 0026-B2990-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-B2990-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Guanfacine is an α2-adrenergic receptor (α2-AR) agonist with anti-hypertensive activity. It shows Ki values of 93, 1,380, and 3,890 nM for α2A-, α2B-, and α2C-ARs, respectively, in a radioligand binding assay. Guanfacine (0.3-5 mg/kg) binds to adrenergic receptors in the central nervous system and lowers blood pressure in hypertensive rats in a dose-dependent manner. It also improves spatial working memory deficits induced by hypobaric hypoxia in rats. Guanfacine is used to treat high blood pressure and attention deficit hyperactivity disorder (ADHD).
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months