Olanzapine

• Description:

  Olanzapine is an antipsychotic agent with anticholinergic properties. It binds to dopamine D1, D2, and D4 receptors (Kis = 31, 11, and 27 nM, respectively) as well as the serotonin (5-HT) receptor subtypes 5-HT2A, 5-HT2C, and 5-HT3 (Kis = 4, 11, and 57 nM, respectively). It also binds to M1 muscarinic acetylcholine, α1-adrenergic, and histamine H1 receptors (Kis = 2, 19, and 7 nM, respectively). Olanzapine induces autophagy, mitochondrial damage and mitophagy in human SH-SY5Y neuronal cell line.

• Shipping Conditions:

  Gel Pack

• Storage Conditions:

  -20ºC

• Shelf Life:

  36 months