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Brequinar Sodium

CAT: 0026-B2637-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B2637-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Brequinar sodium is a potent and selective dihydroorotate dehydrogenase (DHODH) inhibitor (IC50 = ~20 nM). Blocks de novo pyrimidine biosynthesis. Displays minimal inhibition against a panel of >400 kinases. Triggers differentiation of AML cell lines. Causes differentiation and depletion of leukemia-initiating cells in vivo. Antimetabolite.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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