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Ntrk3 Antibody

CAT: 0013-GTR18186723Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18186723Size:100 µg
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Description
TrkCT1 antibody
Product Name Alternative
Rabbit anti-TrkCT1 antibody, rabbit anti-Ntrk3 antibody, TrkCT-1, NT-3 growth factor receptor, GP145-TrkC, Trk-C, ETV6 NTRK3 fusion antibody, GP145 TrkC antibody, GP145TrkC antibody, Neurotrophic tyrosine kinase receptor type 3 antibody, TrkC tyrosine kinase, TrkC NC2
UniProt
Q6VNS1
Reactivity
Human, Mouse
Immunogen
This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the carboxyl terminus of mouse TrkCT1 protein.
Target
Ntrk3
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Concentration
1.0 mg/mL
Dilution
ELISA: 1:5,000 - 1:20,000, IP: 1 μg, WB: 1:1,000 - 1:10,000
Purity
This affinity purified antibody is directed against mouse TrkCT1 protein. The product was affinity purified from monospecific antiserum by immunoaffinity chromatography. A BLAST analysis was used to suggest cross-reactivity with TrkCT1 protein from human, mouse and rat based on 100% homology with the immunizing sequence. Reactivity against homologues from other sources is not known.
Form
Liquid (sterile filtered)
Storage Conditions
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Notes
For research use only.
Applications Notes
This affinity purified antibody has been tested for use in ELISA, IP, and western blotting. Specific conditions for reactivity should be optimized by the end user. While the predicted molecular weight for TrkCT1 is approximately 68 kDa, the protein has been reported to migrate at about 95 kDa on western blots. The molecular weight noted for TrkCT1 depends somewhat upon the cell lysate or extract used for western blotting, and this variation may be due to post-translational modifications of the protein.
Tested Applications
ELISA, IP, WB
NCBI Accession Number
33413429
Host or Source
Rabbit
Preservative
Preservative: 0.01% (w/v) Sodium Azide. Stabilizer: None; Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Isotype
IgG

UniProtKB · Q6VNS1

NT-3 growth factor receptor

NTRK3_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q6VNS1
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Ntrk3
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
2.7.10.1
Processing
Precursor
Secondary accessions
A4QPD0, Q9Z2P9, Q9Z2Q0
Protein keywords

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Molecular function

Developmental proteinKinaseReceptorTransferaseTyrosine-protein kinase

Biological process

DifferentiationNeurogenesis

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

Immunoglobulin domainLeucine-rich repeatRepeatSignalTransmembraneTransmembrane helix

Cellular component

Membrane

Technical term

Reference proteome

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