Mre11a Antibody

CAT: 0013-GTR18186675Size: 100 µgDry Ice: NoHazardous: No

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CAT#:0013-GTR18186675Size:100 µg

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Description

Mre11 antibody

Product Name Alternative

Rabbit anti-Mre11 antibody, Double-strand break repair protein MRE11a, DNA recombination and repair protein, Meiotic recombination 11 homolog A, Mre11a

UniProt

Q61216

Reactivity

Mouse

Immunogen

This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to amino acids 68-706 of mouse Mre11 protein.

Target

Mre11a

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Epigenetics & Chromatin

Concentration

1.05 mg/mL

Dilution

ELISA: 1:10,000 - 1:50,000, WB: 1:500 - 1:2,000

Purity

This affinity purified antibody is directed against mouse Mre11 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross reactivity with Mre11 protein from rat (94% homology) . Based on protein sequence homology also expect partial reactivity against Mre11 homologues from macaque (88%), human (84%) and dog (82%) . This sequence shows less than 75% homology to homologues from bovine, Xenopus, chicken, chimpanzee and zebrafish sources. Reactivity against homologues from other sources is not known.

Form

Liquid (sterile filtered)

Storage Conditions

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Notes

For research use only.

Applications Notes

This affinity purified antibody has been tested for use in ELISA and western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 80 kDa in size corresponding to Mre11 by western blotting in the appropriate cell lysate or extract.

Tested Applications

ELISA, WB

NCBI Accession Number

18202590

Host or Source

Rabbit

Preservative

Preservative: 0.01% (w/v) Sodium Azide. Stabilizer: None; Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Isotype

IgG

UniProtKB · Q61216

Double-strand break repair protein MRE11

MRE11_MOUSE · Mus musculus

View on UniProt ↗

Primary accession: Q61216
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: Mre11
Protein existence: 1: Evidence at protein level
Organism: Mus musculus (Mouse)
Taxonomy ID: 10090
Alternative names: —
EC number: 3.1.-.-
Processing: —
Secondary accessions: Q62430

Protein keywords

PTM

AcetylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Cellular component

ChromosomeNucleusTelomere

Biological process

DNA damageDNA repairMeiosis

Molecular function

EndonucleaseExonucleaseHydrolaseNuclease

Ligand

ManganeseMetal-binding

Technical term

Reference proteome

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