S 3304

CAT: 0804-HY-106992-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-106992-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
S 3304 is a novel matrix metalloproteinases (MMP) inhibitor specific for MMP-2 and MMP-9. S 3304 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
[203640-27-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/S_3304.html
Purity
99.75
Solubility
DMSO : ≥ 83.3 mg/mL
Smiles
O=S(N[C@@H](C(O)=O)CC1=CNC2=C1C=CC=C2)(C3=CC=C(C#CC4=CC=C(C)C=C4)S3)=O
Molecular Formula
C24H20N2O4S2
Molecular Weight
464.56
Precautions
H302, H315, H319, H335
References & Citations
[1]Chiappori AA, et al. A phase I pharmacokinetic and pharmacodynamic study of s-3304, a novel matrix metalloproteinase inhibitor, in patients with advanced and refractory solid tumors. Clin Cancer Res. 2007 Apr 1;13 (7) :2091-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
MMP-9

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