Endothelin-1 (1-31) (Human)

• UNSPSC Description:

  Endothelin-1 (1-31) (Human) is a potent vasoconstrictor and hypertensive agent. Endothelin-1 (1-31) (Human) is derived from the selective hydrolysis of big ET-1 by chymase[1].

• Target Antigen:

  ERK

• Type:

  Peptides

• Related Pathways:

  MAPK/ERK Pathway;Stem Cell/Wnt

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/endothelin-1-1-31-human.html

• Solubility:

  H2O

• Smiles:

  O=C(N[C@@H](CO)C(N[C@@H](CSSC[C@@H](C(N[C@@H](C(C)C)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@H]2CC3=CC=CC=C3)=O)=O)=O)NC4=O)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H](CCSC)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@H]4CCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CSSC[C@@H](C(N[C@@H](CC5=CNC=N5)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC6=CNC7=CC=CC=C67)C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H]([C@H](O)C)C(N8[C@@H](CCC8)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC9=CNC=N9)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N%10[C@@H](CCC%10)C(N[C@@H](CC%11=CC=C(C=C%11)O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC2=O)N

• Molecular Weight:

  3628.16

• References & Citations:

  [1]Matsumoto T, et al. Gender differences in vascular reactivity to endothelin-1 (1-31) in mesenteric arteries from diabetic mice. Peptides. 2008 Aug;29(8):1338-46.|[2]Yoshizumi M, et al. Effect of endothelin-1 (1-31) on human mesangial cell proliferation. Jpn J Pharmacol. 2000 Oct;84(2):146-55.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  133972-52-8