RRD-251
CAT:
804-HY-117737A-01
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
RRD-251
- Product Name Alternative: SR1378
- CAS Number: 72214-67-6
- UNSPSC Description: RRD-251 is an inhibitor of retinoblastoma tumor suppressor protein (Rb)-Raf-1 interaction, with potent anti-proliferative, anti-angiogenic and anti-tumor activities[1].
- Target Antigen: Apoptosis; Raf
- Type: Reference compound
- Related Pathways: Apoptosis;MAPK/ERK Pathway
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/rrd-251.html
- Purity: 99.94
- Solubility: DMSO : 125 mg/mL (ultrasonic)
- Smiles: NC(SCC1=CC=C(Cl)C=C1Cl)=N.[H]Cl
- Molecular Weight: 271.59
- References & Citations: [1]Sandeep Singh, et al. Rb-Raf-1 interaction disruptor RRD-251 induces apoptosis in metastatic melanoma cells and synergizes with dacarbazine. Mol Cancer Ther. 2010 Dec; 9(12): 3330–3341.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported