4’-Hydroxy Trazodone

• UNSPSC Description:

  4’-hydroxy Trazodone is a metabolite of the antidepressant and sedative trazodone. It is an inhibitor of organic anion transporter 3 (OAT3; Ki=16.9 μM) and is selective for OAT3 over OAT1 (Ki=>200 μM).

• Target Antigen:

  OAT

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/4-hydroxy-trazodone.html

• Smiles:

  ClC1=CC(N2CCN(CCCN3N=C(C=CC=C4)N4C3=O)CC2)=CC=C1O

• Molecular Weight:

  387.86

• References & Citations:

  [1]Yamato, et al. Studies on metabolism of trazodone, II. Metabolic fate after intravenous administration and effects on liver microsomal drug-metabolizing enzymes in rats. Xenobiotica 4(12), 765-777 (1974).

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  53818-10-3