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4’-Hydroxy Trazodone

CAT: 0804-HY-W740244Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W740244Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
4’-hydroxy Trazodone is a metabolite of the antidepressant and sedative trazodone. It is an inhibitor of organic anion transporter 3 (OAT3; Ki=16.9 μM) and is selective for OAT3 over OAT1 (Ki=>200 μM) .
CAS Number
53818-10-3
UNSPSC
12352005
Hazard Statement
H302
Target
OAT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/4-hydroxy-trazodone.html
Smiles
ClC1=CC(N2CCN(CCCN3N=C(C=CC=C4)N4C3=O)CC2)=CC=C1O
Molecular Formula
C19H22ClN5O2
Molecular Weight
387.86
Precautions
P264-P270-P330-P501
References & Citations
[1]Yamato, et al. Studies on metabolism of trazodone, II. Metabolic fate after intravenous administration and effects on liver microsomal drug-metabolizing enzymes in rats. Xenobiotica 4 (12), 765-777 (1974) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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