4’-Hydroxy Trazodone

• Description :

  4’-hydroxy Trazodone is a metabolite of the antidepressant and sedative trazodone. It is an inhibitor of organic anion transporter 3 (OAT3; Ki=16.9 μM) and is selective for OAT3 over OAT1 (Ki=>200 μM) .

• UNSPSC :

  12352005

• Hazard Statement :

  H302

• Target :

  OAT

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/4-hydroxy-trazodone.html

• Smiles :

  ClC1=CC(N2CCN(CCCN3N=C(C=CC=C4)N4C3=O)CC2)=CC=C1O

• Molecular Formula :

  C19H22ClN5O2

• Molecular Weight :

  387.86

• Precautions :

  P264-P270-P330-P501

• References & Citations :

  [1]Yamato, et al. Studies on metabolism of trazodone, II. Metabolic fate after intravenous administration and effects on liver microsomal drug-metabolizing enzymes in rats. Xenobiotica 4 (12), 765-777 (1974) .

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [53818-10-3]