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LDN-193665

CAT: 0804-HY-120744Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120744Size:1 Each
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Description
LDN-193665 is a Tau kinase inhibitor with tauopathy-modifying activity. LDN-193665 inhibits Tau phosphorylation, improves tauopathy in animal models, reduces Sarkosyl-insoluble Tau, and restores memory. It may be necessary to simultaneously target multiple kinases to effectively inhibit tauopathies.
CAS Number
1289638-16-9
UNSPSC
12352005
Target
Tau Protein
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ldn-193665.html
Smiles
O=C(C1=C(N)N=C(NC2=CC=CN=C2)S1)C3=CC(F)=CC=C3
Molecular Formula
C15H11FN4OS
Molecular Weight
314.34
References & Citations
[1]Diaminothiazoles modify Tau phosphorylation and improve the tauopathy in mouse models
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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