Akt1&PKA-IN-2
CAT:
804-HY-148868A-01
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Akt1&PKA-IN-2
- CAS Number: 1334108-00-7
- UNSPSC Description: Akt1&PKA-IN-2 ((R)-29) is an inhibitor of PKB/AKT with cyclin-dependent kinase 2 (CDK2) selectivity. Akt1&PKA-IN-2 inhibits AKT1, PKAa and CDK2a with IC50 values of 0.007 µM, 0.01 µM and 0.69 µM, respectively[1].
- Target Antigen: Akt; CDK
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;PI3K/Akt/mTOR
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/akt1-pka-in-2.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(C1=CC2=C(C=NC=C2)C=C1)N[C@H](C3CNC3)C4=CC(Cl)=C(C=C4)Cl
- Molecular Weight: 386.27
- References & Citations: [1]Ashton KS, et al. Design and synthesis of novel amide AKT1 inhibitors with selectivity over CDK2. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5191-6.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported