Benzothiazole

• Description :

  Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent[1][2][3][4].

• CAS Number :

  [95-16-9]

• UNSPSC :

  12352005

• Hazard Statement :

  H301+H311, H319, H332, H402

• Target :

  Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Cancer; Infection; Metabolic Disease; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/benzothiazole.html

• Purity :

  99.04

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  C12=CC=CC=C1SC=N2

• Molecular Formula :

  C7H5NS

• Molecular Weight :

  135.19

• Precautions :

  H301+H311, H319, H332, H402

• References & Citations :

  [1]Ruhi Ali, et al. Biological Aspects of Emerging Benzothiazoles: A Short Review, Journal of Chemistry, vol. 2013, Article ID 345198, 12 pages, 2013.|[2]Côté C, et al. Immunotoxicity of Benzothiazole on Mytilus Edulis Following In Vitro Exposure of Hemocytes. J Xenobiot. 2016 Feb 10;5 (2) :5771.|[3]Singh M, et al. Benzothiazole derivatives bearing amide moiety: potential cytotoxic and apoptosis-inducing agents against cervical cancer. Anticancer Drugs. 2016;27 (6) :519-532.|[4]Ono M, et al. Push-pull benzothiazole derivatives as probes for detecting beta-amyloid plaques in Alzheimer's brains. Bioorg Med Chem. 2009;17 (19) :7002-7007.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported