4-(6-Bromo-2-benzothiazolyl)benzenamine

• UNSPSC Description:

  4-(6-Bromo-2-benzothiazolyl)benzenamine is a β-amyloid PET (positron emission tomography) tracer that can be used in the diagnosis of neurological diseases, such as Alzheimer's and Down's syndrome.

• Target Antigen:

  Amyloid-β; Oxidative Phosphorylation

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease;Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/4-_6-Bromo-2-benzothiazolyl_benzenamine.html

• Purity:

  98.0

• Solubility:

  10 mM in DMSO

• Smiles:

  NC1=CC=C(C2=NC3=CC=C(Br)C=C3S2)C=C1

• Molecular Weight:

  305.19

• References & Citations:

  [1]Klunk W, et al. Benzothiazole derivative compounds, compositions and uses. WO2004083195 A1|[2]Chen YK, et al. Apoptosis induced by 2-aryl benzothiazoles-mediated photodynamic therapy in melanomas via mitochondrial dysfunction. Chem Res Toxicol. 2014 Jul 21;27(7):1187-98.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  566169-97-9