Antifungal agent 115

• UNSPSC Description:

  Antifungal agent 115 (compound 8n) is a non-competitive chitin synthase (CHS) inhibitor with an IC50 of 93 μM. Antifungal agent 115 demonstrates good selectivity and broad-spectrum antifungal activity, exhibiting significant efficacy against drug-resistant fungi. Antifungal agent 115 can be utilized in fungi infection research[1].

• Target Antigen:

  Fungal

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/antifungal-agent-115.html

• Smiles:

  O=C(C1CCN(CC(NC2=CC(NC3=O)=C(C=C2)CC43C(NCC4)=O)=O)CC1)NC5=CC=C([N+]([O-])=O)C=C5C

• Molecular Weight:

  534.56

• References & Citations:

  [1]Long Y, et al. Design and synthesis of spiro[pyrrolidine-3,3'-quinoline]-2,2'-dione derivatives as novel antifungal agents targeting chitin synthase. Eur J Med Chem. 2024 Sep 18;279:116895.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4