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Antifungal agent 75

CAT: 0804-HY-156252Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-156252Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Antifungal agent 75 (compound 6r) is a potent antifungal agent against Candida albicans. Antifungal agent 75 significantly inhibits the formation of C. albicans biofilm, increases the permeability of the cell membrane, reduces the ergosterol level of the cell membrane, damages the membrane structure, and destroys the integrity of the cell structure to exert excellent antifungal activity[1].
CAS Number
3013580-23-6
UNSPSC
12352005
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antifungal-agent-75.html
Solubility
10 mM in DMSO
Smiles
OC(CN1N=CN=C1)(CN(S(=O)(C2=CC=C(Cl)C=C2Cl)=O)CCOC3=CC=C(N4CCN(C(C)=O)CC4)C=C3)C5=CC=C(F)C=C5F
Molecular Formula
C31H32Cl2F2N6O5S
Molecular Weight
709.59
References & Citations
[1]Chunyan Hu, et al. Synthesis and Antifungal Evaluation of New Azole Derivatives against Candida albicans. ACS Med Chem Lett. 2023, 14, 10, 1448-1454.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported