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Tebapivat

CAT: 0804-HY-135884-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-135884-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tebapivat (PKR activator 2) is a potent pyruvate kinase-R (PKR) activator extracted from patent WO2019035863A1, compound 385[1].
CAS Number
2283422-04-6
Product Name Alternative
AG-946; PKR activator 2
UNSPSC
12352005
Target
Pyruvate Kinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/tebapivat.html
Purity
99.66
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C(N(C)C2=C3SC(CC4=NNC=C4)=N2)=C3C=NN1CC5=NC(N)=CC=C5
Molecular Formula
C18H16N8OS
Molecular Weight
392.44
References & Citations
[1]Giovanni Cianchetta, et al. Pyruvate kinase activators for use in treating blood disorders. WO2019035863A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

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