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Nitazoxanide (Standard)

CAT: 0804-HY-B0217R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0217R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nitazoxanide (Standard) is the analytical standard of Nitazoxanide. This product is intended for research and analytical applications. Nitazoxanide (NTZ), an anthelmintic agent, exhibits a broad spectrum of activities against a wide variety of helminths, protozoa, and enteric bacteria infecting animals and humans. Nitazoxanide inhibits Giardia lamblia trophozoite proliferation in axenic culture with an IC50 of 2.4 μM[1]. Nitazoxanide can be used for the research of parasitic gastroenteritis. Nitazoxanide shows anti-Japanese encephalitis virus (JEV) activity in a mouse model[2].
CAS Number
55981-09-4
Product Name Alternative
NTZ (Standard) ; NSC 697855 (Standard)
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Autophagy; Influenza Virus; Parasite; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Autophagy; Others
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/nitazoxanide-standard.html
Smiles
O=C(NC1=NC=C([N+]([O-])=O)S1)C2=CC=CC=C2OC(C)=O
Molecular Formula
C12H9N3O5S
Molecular Weight
307.28
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Rossignol JF, et al. Thiazolides, a new class of anti-influenza molecules targeting viral hemagglutinin at the post-translational level. J Biol Chem. 2009 Oct 23;284 (43) :29798-808.|[2]Zixue Shi, et al. Nitazoxanide inhibits the replication of Japanese encephalitis virus in cultured cells and in a mouse model. Virol J. 2014 Jan 23;11:10.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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