Tyk 2 (Phospho Tyr292) rabbit pAb
CAT:
855-ES20199-02
Size:
100 μL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Tyk 2 (Phospho Tyr292) rabbit pAb
- Description: Tyrosine kinase 2 (TYK2) Homo sapiens This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II Cytokine receptors and promulgate Cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008],
- Synonyms: Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)
- Gene ID: 7297
- UniProt: P29597
- Host: Rabbit
- Species Reactivity: Human, Rat, Mouse,
- Immunogen: Synthesized peptide derived from human Tyk 2 (Phospho Tyr292)
- Clonality: Polyclonal
- Validated Applications: WB, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: WB 1:1000-2000 ELISA 1:5000-20000
- Molecular Weight: 130kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.