Products for Research Use Only
RegisterLogin

Gambogic acid B

CAT: 0804-HY-N10965Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N10965Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Gambogic acid B is an active compound. Gambogic acid B can be isolated from the resin of Garcinia hanburyi.. Gambogic acid B has cytotoxicity against A549, HCT116 and MDA MB 231 cells with IC50 values of 1.60 μM, 6.88 μM and 0.87 μM, respectively[1].
CAS Number
887923-50-4
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gambogic-acid-b.html
Solubility
10 mM in DMSO
Smiles
OC(/C(C)=C\C[C@@]12[C@@]34[C@](C(C5=C(O)C(C=C[C@](C)(O6)CC/C=C(C)/C)=C6C(C/C=C(C)\C)=C5O4)=O)([H])[C@H]([C@@](C[C@@]3([H])C(C)(O2)C)([H])C1=O)OCC)=O
Molecular Formula
C40H50O9
Molecular Weight
674.82
References & Citations
[1]Deng, Yun-Xia et al. Three new xanthones from the resin of Garcinia hanburyi. Planta medica vol. 79,9 (2013) : 792-6.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

Chemical Information

Gambogoic acid B

(Z)-4-[(1S,2S,8R,15S,16S,17S,19R)-16-ethoxy-12-hydroxy-8,21,21-trimethyl-5-(3-methylbut-2-enyl)-8-(4-methylpent-3-enyl)-14,18-dioxo-3,7,20-trioxahexacyclo[15.4.1.02,15.02,19.04,13.06,11]docosa-4(13),5,9,11-tetraen-19-yl]-2-methylbut-2-enoic acid has been reported in Garcinia hanburyi with data available.

CAS Number887923-50-4
PubChem CID101377135
IUPAC Name(Z)-4-[(1S,2S,8R,15S,16S,17S,19R)-16-ethoxy-12-hydroxy-8,21,21-trimethyl-5-(3-methylbut-2-enyl)-8-(4-methylpent-3-enyl)-14,18-dioxo-3,7,20-trioxahexacyclo[15.4.1.02,15.02,19.04,13.06,11]docosa-4(13),5,9,11-tetraen-19-yl]-2-methylbut-2-enoic acid
Molecular FormulaC40H50O9
Molecular Weight674.8
XLogP7.3
Topological Polar Surface Area129
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count10
Heavy Atom Count49
Formal Charge0
Complexity1500
SMILES
CCO[C@H]1[C@@H]2C[C@@H]3[C@]4([C@H]1C(=O)C5=C(O4)C(=C6C(=C5O)C=C[C@@](O6)(C)CCC=C(C)C)CC=C(C)C)[C@](C2=O)(OC3(C)C)C/C=C(/C)\C(=O)O
InChI
InChI=1S/C40H50O9/c1-10-46-34-26-20-27-37(7,8)49-39(35(26)43,19-15-23(6)36(44)45)40(27)29(34)31(42)28-30(41)24-16-18-38(9,17-11-12-21(2)3)47-32(24)25(33(28)48-40)14-13-22(4)5/h12-13,15-16,18,26-27,29,34,41H,10-11,14,17,19-20H2,1-9H3,(H,44,45)/b23-15-/t26-,27-,29-,34-,38+,39-,40-/m0/s1
InChIKey
WMAGOAMNTBBBCL-MXHSWORTSA-N
Chemical Structure
2D Structure
2D structure of Gambogoic acid B
CAS: 887923-50-4
CID: 101377135
Formula: C40H50O9
MW: 674.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight674.8
XLogP37.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count10
Exact Mass674.34548317
Monoisotopic Mass674.34548317
Topological Polar Surface Area129 Ų
Heavy Atom Count49
Formal Charge0
Complexity1500
Isotope Atom Count0
Defined Atom Stereocenter Count7
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-N0087-01Gambogic Acid
HY-N0087R-01Gambogic Acid (Standard)
HY-121833-01Gambogic amide
HY-N5024-01Gambogenic acid
HY-N14662Griseolic acid B
HY-N10665Triptoditerpenic acid B
HY-N6939-01Pseudolaric Acid B
HY-107305Isosalvianolic acid B
HY-122946Pterisolic acid B
HY-N15216Ganolucidic acid B

Alternative Products

CatalogName
2785-25Gambogic acid
MBS5791176Gambogic acid A

Popular Products