Human FGF-8b (Fibroblast Growth Factor-8b)

• Description:

  Human FGF-8b (Fibroblast Growth Factor-8b)_x000D_ Catalog number: B2018710_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 1 ug_x000D_ Molecular Weight or Concentration: ~21 kDa_x000D_ Supplied as: Powder_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -20°C_x000D_ Keywords: FGF-8b, Fibroblast Growth Factor 8b_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Ruohola JK, Viitanen TP, Valve EM, Seppänen JA, Loponen NT, Keskitalo JJ, Lakkakorpi PT, Härkönen PL. Enhanced invasion and tumor growth of fibroblast growth factor 8b-overexpressing MCF-7 human breast cancer cells Cancer Res. 2001 May 15;61(10):4229-37._x000D_ 2: Nilsson EM, Brokken LJ, Narvi E, Kallio MJ, Härkönen PL. Identification of fibroblast growth factor-8b target genes associated with early and late cell cycle events in breast cancer cells Mol Cell Endocrinol. 2012 Jul 6;358(1):104-15._x000D_ 3: Mark RJ, Fuson KS, Keane-Lazar K, May PC. Fibroblast growth factor-8 protects cultured rat hippocampal neurons from oxidative insult Brain Res. 1999 May 29;830(1):88-93._x000D_ 4: Valta MP, Tuomela J, Vuorikoski H, Loponen N, Väänänen RM, Pettersson K, Väänänen HK, Härkönen PL. FGF-8b induces growth and rich vascularization in an orthotopic PC-3 model of prostate cancer J Cell Biochem. 2009 Jul 1;107(4):769-84._x000D_ 5: Elo TD, Valve EM, Seppänen JA, Vuorikoski HJ, Mäkelä SI, Poutanen M, Kujala PM, Härkönen PL. Stromal activation associated with development of prostate cancer in prostate-targeted fibroblast growth factor 8b transgenic mice Neoplasia. 2010 Nov;12(11):915-27._x000D_ 6: Valta MP, Hentunen T, Qu Q, Valve EM, Harjula A, Seppänen JA, Väänänen HK, Härkönen PL. Regulation of osteoblast differentiation: a novel function for fibroblast growth factor 8 Endocrinology. 2006 May;147(5):2171-82._x000D_ 7: Nilsson EM, Brokken LJ, Härkönen PL. Fibroblast growth factor 8 increases breast cancer cell growth by promoting cell cycle progression and by protecting against cell death Exp Cell Res. 2010 Mar 10;316(5):800-12._x000D_ 8: Tanaka A, Furuya A, Yamasaki M, Hanai N, Kuriki K, Kamiakito T, Kobayashi Y, Yoshida H, Koike M, Fukayama M. High frequency of fibroblast growth factor (FGF) 8 expression in clinical prostate cancers and breast tissues, immunohistochemically demonstrated by a newly established neutralizing monoclonal antibody against FGF 8 Cancer Res. 1998 May 15;58(10):2053-6._x000D_ 9: Lin X, Song L, He D, Zeng X, Wu J, Luo W, Yang Q, Wang J, Wang T, Cai J, Lin Y, Lai F, Peng W, Wu X. An FGF8b-mimicking peptide with potent antiangiogenic activity Mol Med Rep. 2017 Jul;16(1):894-900._x000D_ 10: Valve EM, Nevalainen MT, Nurmi MJ, Laato MK, Martikainen PM, Härkönen PL. Increased expression of FGF-8 isoforms and FGF receptors in human premalignant prostatic intraepithelial neoplasia lesions and prostate cancer Lab Invest. 2001 Jun;81(6):815-26. _x000D_ _x000D_ Products Related to Human FGF-8b (Fibroblast Growth Factor-8b) can be found at Proteins

• Short Description:

  Catalog Number: B2018710 (1 ug)_x000D_ FGF-8b is a protein that belongs to the fibroblast growth factor family. It is involved in the regulation of cell proliferation and differentiation in tissues such as the brain, heart, and limbs. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5