Human FGF-18 (Fibroblast Growth Factor-18)

• Description:

  Human FGF-18 (Fibroblast Growth Factor-18)_x000D_ Catalog number: B2018632_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 1 ug_x000D_ Molecular Weight or Concentration: ~20 kDa_x000D_ Supplied as: Powder_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -20°C_x000D_ Keywords: FGF-18, Fibroblast Growth Factor 18_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Tsuchiya Y, Seki T, Kobayashi K, Komazawa-Sakon S, Shichino S, Nishina T, Fukuhara K, Ikejima K, Nagai H, Igarashi Y, Ueha S, Oikawa A, Tsurusaki S, Yamazaki S, Nishiyama C, Mikami T, Yagita H, Okumura K, Kido T, Miyajima A, Matsushima K, Imasaka M, Araki K, Imamura T, Ohmuraya M, Tanaka M, Nakano H. Fibroblast growth factor 18 stimulates the proliferation of hepatic stellate cells, thereby inducing liver fibrosis Nat Commun. 2023 Oct 9;14(1):6304._x000D_ 2: Chen G, An N, Shen J, Chen H, Chen Y, Sun J, Hu Z, Qiu J, Jin C, He S, Mei L, Sui Y, Li W, Chen P, Guan X, Chu M, Wang Y, Jin L, Kim K, Li X, Cong W, Wang X. Fibroblast growth factor 18 alleviates stress-induced pathological cardiac hypertrophy in male mice Nat Commun. 2023 Mar 4;14(1):1235._x000D_ 3: Tong G, Chen X, Lee J, Fan J, Li S, Zhu K, Hu Z, Mei L, Sui Y, Dong Y, Chen R, Jin Z, Zhou B, Li X, Wang X, Cong W, Huang P, Jin L. Fibroblast growth factor 18 attenuates liver fibrosis and HSCs activation via the SMO-LATS1-YAP pathway Pharmacol Res. 2022 Apr;178:106139._x000D_ 4: Zhou Z, Song W, Zhang G, Zhan S, Cai Z, Yu W, He Y. The recombinant human fibroblast growth factor-18 (sprifermin) improves tendon-to-bone healing by promoting chondrogenesis in a rat rotator cuff repair model J Shoulder Elbow Surg. 2022 Aug;31(8):1617-1627._x000D_ 5: Xie Y, Zinkle A, Chen L, Mohammadi M. Fibroblast growth factor signalling in osteoarthritis and cartilage repair Nat Rev Rheumatol. 2020 Oct;16(10):547-564._x000D_ 6: Li J, Wang X, Ruan G, Zhu Z, Ding C. Sprifermin: a recombinant human fibroblast growth factor 18 for the treatment of knee osteoarthritis Expert Opin Investig Drugs. 2021 Sep;30(9):923-930._x000D_ 7: Tong G, Chen Y, Chen X, Fan J, Zhu K, Hu Z, Li S, Zhu J, Feng J, Wu Z, Hu Z, Zhou B, Jin L, Chen H, Shen J, Cong W, Li X. FGF18 alleviates hepatic ischemia-reperfusion injury via the USP16-mediated KEAP1/Nrf2 signaling pathway in male mice Nat Commun. 2023 Sep 30;14(1):6107._x000D_ 8: Tachmazidou I, Hatzikotoulas K, Southam L, Esparza-Gordillo J, Haberland V, Zheng J, Johnson T, Koprulu M, Zengini E, Steinberg J, Wilkinson JM, Bhatnagar S, Hoffman JD, Buchan N, Süveges D; arcOGEN Consortium; Yerges-Armstrong L, Smith GD, Gaunt TR, Scott RA, McCarthy LC, Zeggini E. Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data Nat Genet. 2019 Feb;51(2):230-236._x000D_ 9: Koneczny I, Schulenburg A, Hudec X, Knöfler M, Holzmann K, Piazza G, Reynolds R, Valent P, Marian B. Autocrine fibroblast growth factor 18 signaling mediates Wnt-dependent stimulation of CD44-positive human colorectal adenoma cells Mol Carcinog. 2015 Sep;54(9):789-799._x000D_ 10: Zhou Y, Sun S, Ling T, Chen Y, Zhou R, You Q. The role of fibroblast growth factor 18 in cancers: functions and signaling pathways Front Oncol. 2023 May 9;13:1124520. _x000D_ _x000D_ Products Related to Human FGF-18 (Fibroblast Growth Factor-18) can be found at Proteins

• Short Description:

  Catalog Number: B2018632 (1 ug)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5