Alternariol-d2

• Description:

  Alternariol-d2 is deuterium labeled Alternariol. Alternariol is an orally ingested mycotoxin produced by Alternaria, capable of inhibiting the activity of topoisomerase I and II (topoisomerase I, topoisomerase II) . Alternariol has weak estrogenic (Estrogen Receptor/ERR) and androgen/antiandrogen (Androgen Receptor) effects. Alternariol can induce apoptosis, trigger cell cycle arrest, suppress innate immune responses, and exhibit anti-tumor activity. Alternariol has genotoxic, mutagenic, and endocrine-disrupting effects[1][2][3][4][5][6].

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  Androgen Receptor; Apoptosis; Estrogen Receptor/ERR; Isotope-Labeled Compounds; Topoisomerase

• Type:

  Reference compound

• Related Pathways:

  Apoptosis; Cell Cycle/DNA Damage; Others; Vitamin D Related/Nuclear Receptor

• Field of Research:

  Infection

• Smiles:

  O=C1C2=C(C([2H])=C(C=C2C3=C(C=C(C([2H])=C3O1)O)C)O)O

• Molecular Formula:

  C14H8D2O5

• Molecular Weight:

  260.24

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  Alternaria alternate

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  [2469262-26-6]