Xanthoxyletin

CAT: 0804-HY-N1065-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N1065-01Size:1 mg
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Description
Xanthoxyletin is a coumarin that can be isolated from Genus Zanthoxylum and Clausena. Xanthoxyletin has antioxidant and anti-inflammatory activities. Xanthoxyletin shows cytotoxic effects to cancer cells, and induces apoptosis and necrosis. Xanthoxyletin can be used for the research of cancer and inflammation[1][2].
CAS Number
[84-99-1]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/xanthoxyletin.html
Solubility
10 mM in DMSO
Smiles
O=C(O1)C=CC(C1=C2)=C(OC)C3=C2OC(C)(C)C=C3
Molecular Formula
C15H14O4
Molecular Weight
258.27
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Sanna MD, et al. Histamine H4 receptor stimulation in the locus coeruleus attenuates neuropathic pain by promoting the coeruleospinal noradrenergic inhibitory pathway. Eur J Pharmacol. 2020 Feb 5;868:172859.|[2]Jantamat P, et al. Cytotoxicity and Apoptosis Induction of Coumarins and Carbazole Alkaloids from Clausena harmandiana. Molecules. 2019 Sep 18;24 (18) :3385.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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