Trans-ACPD

• Description :

  Trans-ACPD, a metabotropic receptor agonist, produces calcium mobilization and an inward current in cultured cerebellar Purkinje neurons.

• Product Name Alternative :

  Trans- (±) -ACP

• UNSPSC :

  12352211

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  MGluR

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/trans-ACPD.html

• Concentration :

  10mM

• Purity :

  98.0

• Solubility :

  DMSO : 50 mg/mL (ultrasonic) |H2O : 3.57 mg/mL (ultrasonic)

• Smiles :

  O=C([C@]1(N)C[C@@H](C(O)=O)CC1)O

• Molecular Formula :

  C7H11NO4

• Molecular Weight :

  173.17

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Linden DJ, et al. Trans-ACPD, a metabotropic receptor agonist, produces calcium mobilization and an inward current in cultured cerebellar Purkinje neurons. J Neurophysiol. 1994 May;71 (5) :1992-8.|[2]Littman L, et al. Multiple mechanisms for inhibition of excitatory amino acid receptors coupled to phosphoinositide hydrolysis. J Neurochem. 1992 Nov;59 (5) :1893-904.|[3]Córdova MM, et al. Polysaccharide glucomannan isolated from Heterodermia obscurata attenuates acute and chronic pain in mice. Carbohydr Polym. 2013 Feb 15;92 (2) :2058-64.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  MGluR

• CAS Number :

  [67684-64-4]