cis-ACPD
CAT:
804-HY-19434A
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

cis-ACPD
- CAS Number: 477331-06-9
- UNSPSC Description: cis-ACPD is a potent agonist of NMDA receptor, with an IC50 of 3.3 μM. cis-ACPD is also a selective agonist of group II mGluR, with EC50s of 13 μM and 50 μM for mGluR2 and mGluR4, respectively[1][2].
- Target Antigen: iGluR; mGluR
- Type: Reference compound
- Related Pathways: GPCR/G Protein;Membrane Transporter/Ion Channel;Neuronal Signaling
- Applications: Neuroscience-Neurodegeneration
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/cis-acpd.html
- Solubility: 10 mM in DMSO
- Smiles: O=C([C@]1(N)C[C@H](C(O)=O)CC1)O
- Molecular Weight: 173.17
- References & Citations: [1]Schoepp DD, et, al. In vitro and in vivo pharmacology of trans- and cis-(+-)-1-amino-1,3-cyclopentanedicarboxylic acid: dissociation of metabotropic and ionotropic excitatory amino acid receptor effects. J Neurochem. 1991 May; 56(5):1789-96.|[2]Conti P, et, al. Synthesis and pharmacology of 3-hydroxy-delta2-isoxazoline-cyclopentane analogues of glutamic acid. Farmaco. 2002 Nov; 57(11): 889-95.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported