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DBCO-β-Glu-PEG12-Exatecan

CAT: 0804-HY-160788-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-160788-01Size:1 mg
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Description
DBCO-β-Glu-PEG12-Exatecan (Compound 107) is an inhibitor for topoisomerase I. DBCO-β-Glu-PEG12-Exatecan can be used as a Drug-Linker Conjugate for ADC molecule[1].
CAS Number
3025107-83-6
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC; Topoisomerase
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dbco-β-glu-peg12-exatecan.html
Purity
98.63
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(OCC(C=C1)=CC(CNC(CCNC([C@H](CNC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)NC(CCCCC(N2C3=CC=CC=C3C#CC4=CC=CC=C4C2)=O)=O)=O)=O)=C1O[C@@H]([C@@H]([C@H]5O)O)O[C@@H]([C@H]5O)C(O)=O)N[C@@H]6C(C7=C8CC6)=C(CN9C%10=CC([C@@]%11(O)CC)=C(COC%11=O)C9=O)C%10=NC7=CC(F)=C8C
Molecular Formula
C92H117FN8O30
Molecular Weight
1833.95
References & Citations
[1]BAJJURI K, et al., β-GLUCURONIDE LINKER-PAYLOADS, PROTEIN CONJUGATES THEREOF, AND METHODS THEREOF. WO2024006272.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Camptothecins

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