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LBT-999

CAT: 0804-HY-121810Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-121810Size:1 Each
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Description
LBT-999 is a phenyltropane derivative used for positron emission tomography (PET) exploration of the dopamine transporter (DAT) . It has high affinity binding to DAT on rat striatal membranes and human postmortem brain slices in vitro, high uptake in the striatum in rat and baboon models in vivo, and its binding can be blocked by specific compounds.
CAS Number
877467-20-4
UNSPSC
12352005
Target
Dopamine Transporter
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/lbt-999.html
Smiles
COC([C@@H]1[C@]2([H])N([C@](CC2)([H])C[C@@H]1C3=CC=C(C=C3)C)C/C=C/CF)=O
Molecular Formula
C20H26FNO2
Molecular Weight
331.42
References & Citations
[1]Pharmacological characterization of (E) -N- (4-fluorobut-2-enyl) -2beta-carbomethoxy-3beta- (4'-tolyl) nortropane (LBT-999) as a highly promising fluorinated ligand for the dopamine transporter
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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