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Antifungal agent 122

CAT: 0804-HY-168210Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-168210Size:1 Each
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Description
Antifungal agent 122 (compound 201) is a potent and broad-spectrum antifungal agent. Antifungal agent 122 prevents fungal phase transition and the formation of fungal biofilm. Antifungal agent 122 inhibits CYP3A4-M and CYP3A4-T enzyme activity with IC50 values of 2.11, 4.53 µM. Antifungal agent 122 shows no cytotoxicity[1].
CAS Number
3054212-80-2
UNSPSC
12352005
Target
Cytochrome P450; Fungal
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antifungal-agent-122.html
Smiles
FC1=CC=C([C@@]([C@H](N(C)CC2=CC=C(C#CC3=CC=C(F)C=C3F)C=C2)C)(O)CN4N=CN=C4)C(F)=C1
Molecular Formula
C28H24F4N4O
Molecular Weight
508.51
References & Citations
[1]Sun Y, et al. Discovery of highly potent triazole derivatives with broad-spectrum antifungal activity based on Iodiconazole. Eur J Med Chem. 2024 Oct 9;280:116949.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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