PIP5K1C-IN-1

• UNSPSC Description:

  PIP5K1C-IN-1 (Compound 30) is a potent PIP5K1C inhibitor, with an IC50 of 0.80 nM. PIP5K1C-IN-1 exhibits low total clearance in mice and high levels of kinase selectivity. PIP5K1C-IN-1 can be used for the research of cancer and chronic pain[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/pip5k1c-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N1CC2=C(C31CCC3)C(C(N4)=CC5=C4C=C(Cl)C=C5)=NN2)NC6CC6

• Molecular Weight:

  381.86

• References & Citations:

  [1]Ochiai K, et al. Discovery of Novel Bicyclic Pyrazoles as Potent PIP5K1C Inhibitors. ACS Medicinal Chemistry Letters, 2024.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported