CYLD Antibody [AMM02557G]

• Background:

  Tissue Location: Detected in fetal brain, testis, and skeletal muscle, and at a lower level in adult brain, leukocytes, liver, heart, kidney, spleen, ovary and lung. Isoform 2 is found in all tissues except kidney.

• Synonyms:

  Ubiquitin carboxyl-terminal hydrolase CYLD, 3.4.19.12, Deubiquitinating enzyme CYLD, Ubiquitin thioesterase CYLD, Ubiquitin-specific-processing protease CYLD, CYLD, CYLD1, KIAA0849

• Gene Name:

  CYLD {ECO:0000303|PubMed:12917689, ECO:0000312|HGNC:HGNC:2584}

• Gene ID:

  1540

• UniProt:

  Q9NQC7

• Chromosomal Location:

  Cytoplasm. Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q80TQ2}. Note=Detected at the microtubule cytoskeleton during interphase. Detected at the midbody during telophase. During metaphase, it remains localized to the centrosome but is also present along the spindle (PubMed:25134987) {ECO:0000250|UniProtKB:Q80TQ2, ECO:0000269|PubMed:25134987}

• Applications:

  WB, FC

• Dilution:

  FC--1:25 WB--1:4000

• Function:

  1863608626670046274582372699726627591049292913511831338332185393129176891291769132185393129176902022736619893491182229232019489017495026198934911863608618636086269972662667004627458237275910492699726629291351

• Molecular Weight:

  107316

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CYLD Antibody [AMM02557G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=1540

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9NQC7