USP22 (NM_015276) Human Recombinant Protein

• Background:

  Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  USP3L

• Gene ID:

  23326

• UniProt:

  Q9UPT9

• Accession Number mRNA:

  NM_015276

• Chromosomal Location:

  17p11.2

• Expression System:

  E. coli

• Tag:

  N-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, 8M Urea, pH8.0.

• Function:

  Protease

• Molecular Weight:

  59.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  USP22

• Species:

  Human

• Protein ID:

  NP_056091

• Overview:

  Purified recombinant protein of Human ubiquitin specific peptidase 22 (USP22), full length, with N-terminal HIS tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/23326

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UPT9

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_015276

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_056091