M-CSF Antibody (Center) [APR05800G]

• Synonyms:

  Macrophage colony-stimulating factor 1, CSF-1, M-CSF, MCSF, Lanimostim, Processed macrophage colony-stimulating factor 1, CSF1

• Gene Name:

  CSF1

• Gene ID:

  1435

• UniProt:

  P09603

• Chromosomal Location:

  Cell membrane; Single-pass type I membrane protein

• Applications:

  FC, IF, IHC-P, WB

• Dilution:

  WB--1:1000 FC--1:10~50 IF--1:10~50 IHC-P--1:100~500

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

• Function:

  Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.

• Molecular Weight:

  60179

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality M-CSF Antibody (Center) [APR05800G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=1435

• Uniprot URL:

  https://www.uniprot.org/uniprot/P09603