RASSF7 Antibody (C-term) [APR04156G]

• Synonyms:

  Ras association domain-containing protein 7, HRAS1-related cluster protein 1, RASSF7, C11orf13, HRC1

• Gene Name:

  RASSF7

• Gene ID:

  8045

• UniProt:

  Q02833

• Chromosomal Location:

  Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with gamma-tubulin

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization.

• Molecular Weight:

  39945

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RASSF7 Antibody (C-term) [APR04156G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=8045

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q02833