RASSF7 (NM_003475) Human Recombinant Protein

• Background:

  Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  C11orf13; CFAP88; FAP88; HRAS1; HRC1

• Gene ID:

  8045

• UniProt:

  Q02833, A0A024RCE4

• Accession Number mRNA:

  NM_003475

• Chromosomal Location:

  11p15.5

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  39.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  RASSF7

• Species:

  Human

• Protein ID:

  NP_003466

• Overview:

  Recombinant protein of human Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 (RASSF7), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/8045

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q02833

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003475

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003466