GFER Antibody (C-term) [APR03596G]

• Background:

  Tissue Location: Ubiquitously expressed. Highest expression in the testis and liver and low expression in the muscle

• Synonyms:

  FAD-linked sulfhydryl oxidase ALR, Augmenter of liver regeneration, hERV1, Hepatopoietin, GFER, ALR, HERV1, HPO

• Gene Name:

  GFER

• Gene ID:

  2671

• UniProt:

  P55789

• Chromosomal Location:

  [Isoform 1]: Mitochondrion intermembrane space. Mitochondrion

• Applications:

  WB, FC

• Dilution:

  WB--1:1000 FC--1:10~50

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

• Function:

  [Isoform 1]: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen.

• Molecular Weight:

  23449

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GFER Antibody (C-term) [APR03596G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=2671

• Uniprot URL:

  https://www.uniprot.org/uniprot/P55789