Contulakin G

• UNSPSC Description:

  Contulakin G is an O-glycosylated invertebrate neurotensin. Contulakin-G is a weaker agonist for the neurotensin receptor. Contulakin G is also a potent antinociceptive agent[1][2].

• Target Antigen:

  Neurotensin Receptor

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/contulakin-g.html

• Solubility:

  H2O

• Smiles:

  CC(N[C@@H]1[C@H]([C@H]([C@H](O[C@@H]1O[C@H](C)[C@H](NC([C@H](C)NC([C@H](CC(N)=O)NC([C@H](CO)NC(CNC(CNC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@H](CO)NC([C@H]2NC(CC2)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N3[C@@H](CCC3)C(N[C@H](C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(O)=O)CC(C)C)=O)=O)CC4=CC=C(C=C4)O)=O)=O)=O)=O)CO)O)O[C@@H]5O[C@@H]([C@@H]([C@@H]([C@H]5O)O)O)CO)=O

• Molecular Weight:

  2070.17

• References & Citations:

  [1]Lee HK, et al. A marine analgesic peptide, Contulakin-G, and neurotensin are distinct agonists for neurotensin receptors: uncovering structural determinants of desensitization properties. Front Pharmacol. 2015 Feb 10;6:11.|[2]Allen JW, et al. An assessment of the antinociceptive efficacy of intrathecal and epidural contulakin-G in rats and dogs. Anesth Analg. 2007 Jun;104(6):1505-13, table of contents.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  229180-41-0