Ethylenediaminetetraacetic acid (tetrasodium)

Ethylenediaminetetraacetic acid (tetrasodium)

• CAS Number: 64-02-8
• UNSPSC Description: Ethylenediaminetetraacetic acid (EDTA) tetrasodium is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid tetrasodium has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid tetrasodium decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid tetrasodium can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid tetrasodium can be used for coronary artery disease and neural system disease research[1][2][3][4][5][6][7].
• Target Antigen: Bacterial; Biochemical Assay Reagents; SOD
• Type: Biochemical Assay Reagents
• Related Pathways: Anti-infection;Immunology/Inflammation;Others
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease; Cardiovascular Disease; Cancer
• Assay Protocol: https://www.medchemexpress.com/ethylenediaminetetraacetic-acid-tetrasodium.html
• Purity: 99.6
• Solubility: H2O : 125 mg/mL (ultrasonic)
• Smiles: O=C(O[Na])CN(CCN(CC(O[Na])=O)CC(O[Na])=O)CC(O[Na])=O
• Molecular Weight: 380.17
• References & Citations: [1]Chumanov RS, et al. Artifact-inducing enrichment of ethylenediaminetetraacetic acid and ethyleneglycoltetraacetic acid on anion exchange resins. Anal Biochem. 2011 May 1;412(1):34-9.|[2]Banfi G, et al. The role of ethylenediamine tetraacetic acid (EDTA) as in vitro anticoagulant for diagnostic purposes. Clin Chem Lab Med. 2007;45(5):565-76.|[3]Ibad A, et al. Chelation therapy in the treatment of cardiovascular diseases. J Clin Lipidol. 2016 Jan-Feb;10(1):58-62.|[4]Gray GW, et al. The effect of ethylenediaminetetra-acetic acid on the cell walls of some gram-negative bacteria. J Gen Microbiol. 1965 Jun;39(3):385-99. |[5]González-Cuevas J, et al. Ethylenediaminetetraacetic acid induces antioxidant and anti-inflammatory activities in experimental liver fibrosis. Redox Rep. 2011;16(2):62-70. |[6]Naghipour D, et al. Remediation of heavy metals contaminated silty clay loam soil by column extraction with ethylenediaminetetraacetic acid and nitrilo triacetic acid[J]. Journal of Environmental Engineering, 2017, 143(8): 04017026.|[7]Deai M, et al. Ethylenediaminetetraacetic acid (EDTA) enhances cAMP production in human TDAG8-expressing cells. Biochem Biophys Res Commun. 2022 Oct 20;626:15-20.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
• Clinical Information: Phase 4