HEMGN Antibody (C-term) [APR16681G]

• Background:

  Tissue Location: Expressed in hematopoietic precursor cells, thyroid and spermatids (at protein level) . Expressed in bone marrow, testis, thymus. Expressed in prostate cancer and ovarian cancer. Also expressed in thymus and thyroid tumors, non-Hodgkin lymphoma, various leukemia cell lines, peripheral blood mononuclear cells (PBMCs) and bone marrow mononuclear cells (BMMCs) of patients with leukemia

• Synonyms:

  Hemogen, Erythroid differentiation-associated gene protein, EDAG-1, Hemopoietic gene protein, Negative differentiation regulator protein, HEMGN, EDAG, NDR

• Gene Name:

  HEMGN

• Gene ID:

  55363

• UniProt:

  Q9BXL5

• Chromosomal Location:

  Nucleus.

• Applications:

  WB

• Dilution:

  WB--1:2000

• Function:

  Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB) .

• Molecular Weight:

  55341

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HEMGN Antibody (C-term) [APR16681G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=55363

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9BXL5