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AubipyOMe

CAT: 0804-HY-138869-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-138869-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AubipyOMe serves as a potent inhibitor of tartrate-resistant acid phosphatase (TRAP/ACP5), a metalloenzyme found in activated osteoclasts and macrophages, demonstrating IC50 values of 1.3 μM for TRAP5a and 1.8 μM for TRAP5b, while effectively inhibiting TRAP activity in extracts from murine macrophages and human lung tissue.
CAS Number
1221591-26-9
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aubipyome.html
Purity
99.0
Smiles
[F-][P+5]([F-])([F-])([F-])([F-])[F-].[Cl-][Au+3]1([N]2=CC=C(C=C2C3=[N]1C=CC(OC)=C3)OC)[Cl-]
Molecular Formula
C12H12AuCl2F6N2O2P
Molecular Weight
629.07
References & Citations
[1]Molecular and functional properties of P2X receptorsrecent progress and persisting challenges|[2]Covalent binding of 3'-O- (4-benzoyl) benzoyl adenosine 5'-triphosphate (BzATP) to the isolated alpha and beta subunits and the alpha 3 beta 3 core complex of TF1|[3]P2X7 receptor inhibition increases CNTF in the subventricular zone, but not neurogenesis or neuroprotection after stroke in adult mice|[4]Osmotic surveillance mediates rapid wound closure through nucleotide release|[5]Benzophenone-ATP: A photoaffinity label for the active site of ATPasesTest1986|[6]Receptor-independent effects of 2 (3) -O- (4-benzoylbenzoyl) ATP triethylammonium salt on cytosolic p|[7]P2times 7 Receptor in the Kidneys of Diabetic Rats Submitted to Aerobic Training or to N-Acetylcysteine Supplementation|[8]Diabetes-induced Neuropathic Mechanical Hyperalgesia Depends on P2X4 Receptor Activation in Dorsal Root Ganglia
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
GTR19239634-01AubipyOMe

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