MAP3K13 (LZK) Antibody (C-term) (S869) [APR17285G]

• Background:

  Tissue Location: Expressed in the adult brain, liver, placenta and pancreas, with expression strongest in the pancreas

• Synonyms:

  HGNC:6852

• Gene Name:

  HGNC:6852

• Gene ID:

  9175

• UniProt:

  O43283

• Chromosomal Location:

  Cytoplasm. Membrane; Peripheral membrane protein

• Applications:

  WB, IHC-P

• Dilution:

  WB--1:1000 IHC-P--1:100~500

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB- containing complex that phosphorylates inhibitors of NF-kappa-B.

• Molecular Weight:

  108296

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MAP3K13 (LZK) Antibody (C-term) (S869) [APR17285G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=9175

• Uniprot URL:

  https://www.uniprot.org/uniprot/O43283