MAP3K13 (LZK) Antibody (C-term) [AMM22159G]

• Background:

  Tissue Location: Expressed in the adult brain, liver, placenta and pancreas, with expression strongest in the pancreas

• Synonyms:

  HGNC:6852

• Gene Name:

  HGNC:6852

• Gene ID:

  9175

• UniProt:

  O43283

• Chromosomal Location:

  Cytoplasm. Membrane; Peripheral membrane protein

• Applications:

  IF, WB

• Dilution:

  WB--1:500

• Form:

  Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

• Function:

  Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB- containing complex that phosphorylates inhibitors of NF-kappa-B.

• Molecular Weight:

  108296

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MAP3K13 (LZK) Antibody (C-term) [AMM22159G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=9175

• Uniprot URL:

  https://www.uniprot.org/uniprot/O43283