Synphilin-1 (SNCAIP) Antibody (C-term) [APR13635G]

• Background:

  Tissue Location: Detected in brain (at protein level) . Widely expressed, with highest levels in brain, heart and placenta

• Synonyms:

  Synphilin-1, Sph1, Alpha-synuclein-interacting protein, SNCAIP

• Gene Name:

  SNCAIP

• Gene ID:

  9627

• UniProt:

  Q9Y6H5

• Chromosomal Location:

  Cytoplasm. Note=Detected in cytoplasmic inclusion bodies, together with SNCA

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

• Function:

  Isoform 2 inhibits the ubiquitin ligase activity of SIAH1 and inhibits proteasomal degradation of target proteins. Isoform 2 inhibits autoubiquitination and proteasomal degradation of SIAH1, and thereby increases cellular levels of SIAH. Isoform 2 modulates SNCA monoubiquitination by SIAH1.

• Molecular Weight:

  100409

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Synphilin-1 (SNCAIP) Antibody (C-term) [APR13635G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=9627

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9Y6H5