Synphilin 1 (SNCAIP) (NM_005460) Human Recombinant Protein

• Background:

  This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

• Synonyms:

  Sph1; SYPH1

• Gene ID:

  9627

• UniProt:

  Q9Y6H5

• Accession Number mRNA:

  NM_005460

• Chromosomal Location:

  5q23.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Parkinson's disease

• Field of Research:

  Parkinson's disease

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  100.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  SNCAIP

• Species:

  Human

• Protein ID:

  NP_005451

• Overview:

  Recombinant protein of human synuclein, alpha interacting protein (SNCAIP)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/9627

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9Y6H5

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_005460

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_005451