KIRREL Antibody (C-term) [APR17029G]

• Background:

  Tissue Location: Abundantly expressed in kidney. Specifically expressed in podocytes of kidney glomeruli

• Synonyms:

  Kin of IRRE-like protein 1, Kin of irregular chiasm-like protein 1, Nephrin-like protein 1, KIRREL, KIRREL1, NEPH1

• Gene Name:

  HGNC:15734

• Gene ID:

  55243

• UniProt:

  Q96J84

• Chromosomal Location:

  Cell membrane; Single-pass type I membrane protein. Note=Predominantly located at podocyte slit diaphragm

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  Plays a significant role in the normal development and function of the glomerular permeability. Signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1 (By similarity) .

• Molecular Weight:

  83536

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KIRREL Antibody (C-term) [APR17029G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=55243

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q96J84