CPEB1 Antibody (C-term) [APR11651G]

• Background:

  Tissue Location: Isoform 1 is expressed in immature oocytes, ovary, brain and heart. Isoform 2 is expressed in brain and heart. Isoform 3 and isoform 4 are expressed in brain. Expressed in breast tumors and several tumor cell lines.

• Synonyms:

  Cytoplasmic polyadenylation element-binding protein 1, CPE-BP1, CPE-binding protein 1, h-CEBP, hCPEB-1, CPEB1, CPEB

• Gene Name:

  CPEB1

• Gene ID:

  64506

• UniProt:

  Q9BZB8

• Chromosomal Location:

  Cytoplasm. Nucleus Cytoplasm, P-body. Cytoplasmic granule. Cell junction, synapse Membrane. Cell junction, synapse, postsynaptic density Cell projection, dendrite. Note=Continuously shuttling between nucleus and cytoplasm (PubMed:18923137) . Also found in stress granules. Recruited to stress granules (SGs) upon arsenite treatment In dendrites (By similarity) . Localizes in synaptosomes at dendritic synapses of neurons (By similarity) . Strongly enriched in postsynaptic density (PSD) fractions (By similarity) . Transported into dendrites in a microtubule-dependent fashion and colocalizes in mRNA-containing particles with TACC3, dynein and kinesin (By similarity) . Membrane- associated (By similarity) . Colocalizes at excitatory synapses with members of the polyadenylation and translation complex factors (CPSF, APLP1, TACC3, AURKA, SYP, etc.) including CPE-containing RNAs (By similarity) . {ECO:0000250, ECO:0000269|PubMed:18923137}

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  2499096726398195

• Molecular Weight:

  62595

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CPEB1 Antibody (C-term) [APR11651G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=64506

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9BZB8