Products for Research Use Only
RegisterLogin

Sudan IV

CAT: 0804-HY-D0932Size: 500 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-D0932Size:500 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Sudan IV is an agonist of the aryl hydrocarbon receptor (AhR) that activates downstream signaling pathways and induces CYP1A1 expression. Sudan IV promotes CYP1A1 gene transcription by activating AhR-ARNT heterodimers and binding to exogenous response elements (XREs) on DNA, thereby enhancing drug metabolizing enzyme activity. Sudan IV can be used to study the toxicity mechanisms of industrial dyes and the effects of interactions with serum proteins (such as bovine serum albumin (BSA) ) on their distribution in vivo. Sudan IV is a fat-soluble diazo dye that can be used to stain lipids, triglycerides, and lipoproteins on frozen sections[1][2][3][4].
CAS Number
85-83-6
Product Name Alternative
Solvent Red 24; C.I. 26105
UNSPSC
12171500
Hazard Statement
H317
Target
Aryl Hydrocarbon Receptor; Biochemical Assay Reagents; Cytochrome P450
Type
Dye Reagents
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/sudan-iv.html
Purity
98.0
Solubility
DMSO : < 1 mg/mL
Smiles
OC1=CC=C2C=CC=CC2=C1/N=N/C3=CC=C(/N=N/C4=CC=CC=C4C)C=C3C
Molecular Formula
C24H20N4O
Molecular Weight
380.44
Precautions
H317
References & Citations
[1]Refat NA, et al. The induction of cytochrome P450 1A1 by sudan dyes. J Biochem Mol Toxicol. 2008 Mar-Apr;22 (2) :77-84.|[2]Lu D, et al. Binding of Sudan II and Sudan IV to bovine serum albumin: comparison studies. Food Chem Toxicol. 2011 Dec;49 (12) :3158-64.|[3]Huang ST, et al. An ultrasensitive and selective fluorescence assay for Sudan I and III against the influence of Sudan II and IV. Biosens Bioelectron. 2013 Apr 15;42:136-40.|[4]Pérez-Sanz F, Riquelme-Pérez M, Martínez-Barba E, de la Peña-Moral J, Salazar Nicolás A, Carpes-Ruiz M, Esteban-Gil A, Legaz-García MDC, Parreño-González MA, Ramírez P, Martínez CM. Efficiency of Machine Learning Algorithms for the Determination of Macrovesicular Steatosis in Frozen Sections Stained with Sudan to Evaluate the Quality of the Graft in Liver Transplantation. Sensors (Basel) . 2021 Mar 12;21 (6) :1993.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Isoform
CYP1

Related Products

CatalogName
HY-D0931-01Sudan III
HY-D0928-01Sudan II
HY-D0024-01Sudan I
HY-145612-01Sudan red 7B
HY-119987-01Sudan orange G
HY-161545Sudan I/BSA
HY-D0931R-01Sudan III (Standard)
HY-152041SSudan II-d6
HY-W019776-01Sudan I-d5
HY-161584Sudan I/KLH

Alternative Products

CatalogName
AG032SudanⅠ
289227-01Sudan I (Sudan Yellow)
SB0914Sudan IV (sudan red 4)
C7176-500Sudan I
596123Sudan III
RG-A260945-01Sudan Iv
TRC-S688890-1GSudan II
TRC-S688910-1GSudan Black
evd-079Ebola Sudan
FS27925-01Sudan R

Popular Products