IsocitRe dehydrogenase (IDH3) Antibody (C-term) [APG02912G]

• Synonyms:

  Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitric dehydrogenase subunit alpha, NAD (+) -specific ICDH subunit alpha, IDH3A

• Gene Name:

  IDH3A

• Gene ID:

  3419

• UniProt:

  P50213

• Chromosomal Location:

  Mitochondrion.

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

• Function:

  Catalytic subunit of the enzyme which catalyzes the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.

• Molecular Weight:

  39592

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IsocitRe dehydrogenase (IDH3) Antibody (C-term) [APG02912G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=3419

• Uniprot URL:

  https://www.uniprot.org/uniprot/P50213