PC5-VC-PAB-MMAE

PC5-VC-PAB-MMAE

• CAS Number: 2922216-98-4
• UNSPSC Description: PC5-VC-PAB-MMAE consists the ADCs linker (PC5-VC-PAB) and potent tubulin inhibitor (MMAE). PC5-VC-PAB-MMAE is a agent-linker conjugate for ADC[1].
• Target Antigen: Drug-Linker Conjugates for ADC; Microtubule/Tubulin
• Type: ADC Related
• Related Pathways: Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pc5-vc-pab-mmae.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCC(OC4=C(C(F)=C(C(F)=C4F)F)F)=O)=O)=O)=O)=O)=O)=O)=O)OC)=O
• Molecular Weight: 1403.57
• References & Citations: [1]Zhaohui LI, et al. Anti-cd39 antibody-drug conjugate and use thereof. China, WO2023051712. 2023-04-06.
• Shipping Conditions: Blue Ice
• Clinical Information: No Development Reported