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Primidone-d5

CAT: 0804-HY-B0339S-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B0339S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Primidone-d5 is the deuterium labeled Primidone. Primidone is the orally active inhibitor for TRPM3 (IC50 = 0.6 μM), RIP kinase and voltage-gated sodium channel, and the antagonist for GABA receptor. Primidone can be used as the analgesic and anticonvulsant agent[1][2][3].
CAS Number
[73738-06-4]
UNSPSC
12352005
Target
GABA Receptor; Isotope-Labeled Compounds; Necroptosis; RIP kinase; Sodium Channel; TRP Channel
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Inflammation/Immunology; Neurological Disease
Purity
99.00
Solubility
10 mM in DMSO|DMSO : 50mg/mL (ultrasonic) |H2O : ≥ 0.67mg/mL
Smiles
[2H]C([2H])([2H])C([2H])([2H])C1(C2=CC=CC=C2)C(NCNC1=O)=O
Molecular Formula
C12H9D5N2O2
Molecular Weight
223.28
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Kevin Kwong, et al. Voltage-gated sodium channels. Curr Opin Pharmacol. 2015 Jun;22:131-9
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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