Primidone-d5

• UNSPSC Description:

  Primidone-d5 is the deuterium labeled Primidone. Primidone is a potent anticonvulsant agent of the barbiturate class. Primidone is a neuronal voltage-gated sodium channel (VGSC) blocker and can be used for the study of epilepsy, essential tremor, and Psychiatric disorders[1].

• Target Antigen:

  Isotope-Labeled Compounds; Sodium Channel

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Membrane Transporter/Ion Channel;Others

• Field of Research:

  Neurological Disease

• Purity:

  99.00

• Solubility:

  10 mM in DMSO

• Smiles:

  [2H]C([2H])([2H])C([2H])([2H])C1(C2=CC=CC=C2)C(NCNC1=O)=O

• Molecular Weight:

  223.28

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Kevin Kwong, et al. Voltage-gated sodium channels. Curr Opin Pharmacol. 2015 Jun;22:131-9

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  73738-06-4