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H-Pro-Lys-OH

CAT: 0804-HY-P4558Size: 1 EachDry Ice: NoHazardous: No
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Description
H-Pro-Lys-OH is a dipeptide containing proline and lysine, which can serve as a substrate for iminodipeptidase (prolinase) . H-Pro-Lys-OH can also be used for the synthesis of polypeptides[1][2].
CAS Number
71227-70-8
UNSPSC
12352209
Target
Dipeptidyl Peptidase
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/h-pro-lys-oh.html
Solubility
10 mM in DMSO
Smiles
NCCCC[C@@H](C(O)=O)NC([C@@H]1CCCN1)=O
Molecular Formula
C11H21N3O3
Molecular Weight
243.30
References & Citations
[1]Mayer H, et al. The cleavage of prolyl peptides by kidney peptidases. Purification of iminodipeptidase (Prolinase) . Hoppe Seylers Z Physiol Chem. 1973 Apr;354 (4) :371-9.|[2]Mentlein R. Proline residues in the maturation and degradation of peptide hormones and neuropeptides. FEBS Lett. 1988 Jul 18;234 (2) :251-6.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

Chemical Information

Pro-Lys

Pro-Lys is a dipeptide formed from L-proline and L-lysine residues. It has a role as a metabolite.

CAS Number71227-70-8
PubChem CID9209431
IUPAC Name(2S)-6-amino-2-[[(2S)-pyrrolidine-2-carbonyl]amino]hexanoic acid
Molecular FormulaC11H21N3O3
Molecular Weight243.30
XLogP-4
Topological Polar Surface Area104
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count7
Heavy Atom Count17
Formal Charge0
Complexity271
SMILES
C1C[C@H](NC1)C(=O)N[C@@H](CCCCN)C(=O)O
InChI
InChI=1S/C11H21N3O3/c12-6-2-1-4-9(11(16)17)14-10(15)8-5-3-7-13-8/h8-9,13H,1-7,12H2,(H,14,15)(H,16,17)/t8-,9-/m0/s1
InChIKey
RVQDZELMXZRSSI-IUCAKERBSA-N
Chemical Structure
2D Structure
2D structure of Pro-Lys
CAS: 71227-70-8
CID: 9209431
Formula: C11H21N3O3
MW: 243.30
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight243.30
XLogP3-4
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count7
Exact Mass243.15829154
Monoisotopic Mass243.15829154
Topological Polar Surface Area104 Ų
Heavy Atom Count17
Formal Charge0
Complexity271
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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4016384.0050H-Lys-Pro-OH
G-3040.0250H-Pro-Lys-OH
GTR19113247-01H-Pro-Lys-OH TFA
H-2558.0050H-Lys-Pro-Tyr-OH
H-4790.0250H-Pro-Phe-Lys-OH
H-5045.0100H-Thr-Lys-Pro-Pro-Arg-OH
FP108159H-Pro-Lys-OH acetate salt
FL108285-01H-Lys-Pro-OH hydrochloride salt
H-4785.0250H-Pro-Phe-Gly-Lys-OH
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